• Canadian Brand Names: PMS-Trihexyphenidyl;Trihexyphen;Trihexyphenidyl
• Mexican Brand Names: Hipokinon
• Pharmacologic Category: Anti-Parkinson's Agent, Anticholinergic;Anticholinergic Agent

• This medicine is used to treat Parkinson's disease.
• This medicine is used to treat side effects caused by some medicine used to treat schizophrenia.
• Trihexyphenidyl improves the chemical balance in the brain.

How to take

• Take this medicine with food.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• A liquid (elixir) is available if you cannot swallow pills.
• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

Missed Dose

• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.

Storage

• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.

Avoid

• If you have an allergy to trihexyphenidyl or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

Precautions

• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you are a male with problems urinating, talk with healthcare provider.
• If you have glaucoma, talk with healthcare provider.
• If you have heart disease, talk with healthcare provider.
• If you have an intestinal blockage, talk with healthcare provider.
• If you have stomach ulcers, talk with healthcare provider.
• If you have urinary tract blockage, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor).
• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
• Be careful in hot weather. Drink plenty of fluids to prevent dehydration.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.

Side Effects

• Dizziness.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Blurred vision.
• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Monitoring

• Change in condition being treated. Is it better, worse, or about the same?
• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
• Follow up with healthcare provider.

Contact a healthcare provider

• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Severe dizziness or passing out.
• Significant change in thinking clearly and logically.
• Unable to pass urine.
• Severe constipation.
• Any rash.
• No improvement in condition or feeling worse.

General Statements

• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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